PI Krekelberg received a new four-year grant from the Obama BRAIN Initiative to study the Neural Mechanisms of Transcranial Current Stimulation.

In transcranial current stimulation two or more electrodes are placed on the head and low level currents are passed between them. This technique is increasingly being used in the clinic to alleviate the symptoms of depression, reduce epileptic seizures, and even to increase cognitive performance in healthy volunteers. However, very little is known about the nature of the neural changes induced by transcranial currents. This project combines intracranial recordings in animals with transcranial stimulation to determine how current strength, duration, and pattern affect neural information processing. These insights are essential for the rational design of electrotherapy.

Read more about this research here.